Lab 204

Tel.: (0049) 221-470-3073

Fax : (0049) 221 470 5057




Research: GST-Transferase inhibitorisch aktive Peroxide / Collaborative project with the Institute of Pharmacology and the Faculty of Applied Sciences (FH Köln)

visit the video presentation:

"Synthetic approaches to mono- and bicyclic perortho-esters with a central 1,2,4-trioxane ring as the privileged lead structure in antimalarial and antitumor-active peroxides and clarification of the peroxide relevance" Axel Griesbeck, Maria Bräutigam, Margarethe  Kleczka und Angela Raabe, Molecules 2017, 22, 110, doi: 10.3390/molecules22010119.

"Selective Inhibitors of Glutathione Transferase P1 with Trioxane Structure as Anticancer Agents" Maria Bräutigam, Nicole Teusch, Tobias Schenk, Miriam Sheikh, Rocky Z. Aricioglu, Swantje H. Borowski, Jörg-Martin Neudörfl, Ulrich Baumann, Axel G. Griesbeck und Markus Pietsch, ChemMedChem 2015, 10, 629-639. DOI: 10.1002/cmdc.201402553. BACKSIDE COVER

"Model studies on peroxidic glutathione transferase (GST) inhibitors: C5-methylated 1,2,4-trioxanes with C6-acrylate side chains" Axel G. Griesbeck, Andreas Maaßen, Maria Bräutigam und Markus Pietsch, Eur. J. Org. Chem. 2015,
4349-4352. see FRONT COVER of the EJOC issue 22.

"Synthetic Organic photochemistry – Grown up and applicable for life sciences" Axel G. Griesbeck, Maria Bräutigam, Sebastian Hanft, Margarethe Kleczka, Sabrina Molitor, Melissa Reckenthäler und Sarah Sillner, European Photochemical Society Newsletter 2013, 12-22.