Lab 215 Tel.: (0221) 470 3074 Fax : (0221) 470 5057 Email: tamer.el-idreesy@uni-koeln.de

Research: Photooxygenation, Singlet Oxygen Chemistry, Synthesis of Allylic

Hydroperoxides and 1,2,4-trioxanes, Solid-State Photooxygenation

KURT-ALDER AWARD of the Cologne University for the best Ph.D. Thesis in 2005

Publications

Convenient Synthesis of anti-Malaria active 1,2,4-Trioxanes via Photooxygenation of a Chiral Allylic Alcohol, Axel G. Griesbeck, Tamer El-Idreesy, Maren Fiege and Reto Brun Org. Lett. 2002, 4, 4193-4195.

Photooxygenation of Allylic Alcohols: Comparison of Unfunctionalized Alkenes, and Acetates with Prenol-Type Allylic Alcoholes and Acetates, Axel G. Griesbeck, Waldemar Adam, Anna Bartoschek and Tamer T. El-Idreesy, Photochem. Photobiol. Sci. 2003, 2, 877-881.

Ene-Reactions with Singlet Molecular Oxygen” Axel G. Griesbeck, Waldemar Adam, Tamer El-Idreesy und Oliver Krebs in CRC Handbook of  Organic Photochemistry and Photobiology, William M. Horspool, F. Lenci (eds.), CRC Press: Boca Raton 2004, 8, 1-20.

Photooxygenation in polystyrene beads with covalently and non-covalently bound tetraarylstyrene sensitizers, Axel G. Griesbeck, Tamer T. El-Idreesy, and Anna Bartoschek Adv. Synthesis & Catalysis 2004, 346, 245-251.

Photooxygenation in polymer matrices: en route to highly active antimalarial peroxides Axel G. Griesbeck, Tamer T. El-Idreesy und Anna Bartoschek, Pure & Applied Chemistry 2005, 77, 1059-1074

"Novel spiro-anellated 1,2,4-trioxanes with high in-vitro antimalarial activities" Axel G. Griesbeck, Tamer T. El-Idreesy, Lars-Oliver Höinck, Johann Lex and Reto Brun, Bioorg. Med. Chem. Lett. 2005, 15, 595-597.

"Solvent-free photooxygenation of 5-methoxy oxazoles in polystyrene nanocontainers doped with tetrastyrylporphyrine and protoporhyrine IX" Axel G. Griesbeck and Tamer T. El-Idreesy, Photochem. Photobiol. Sci. 2005, 4, 205-209.

"A family of new 1,2,4-trioxanes by photooxygenation of allylic alcohols in sensitizer-doped polymers and secondary reactions" Anna Bartoschek, Tamer T. El-Idreesy, Axel G. Griesbeck, Lars-Oliver Höinck, Johann Lex, Claus Miara, and Jörg M. Neudörfl, Synthesis 2005, 2433-2444.

"Type II photooxygenation in polymer matrices for the synthesis of new antimalarial peroxides” Axel G. Griesbeck, Anna Bartoschek, Tamer T. El-Idreesy, O. Höinck, and Claus Miara, J. Mol. Cat. A: Chem. 2006, 251, 41-48.

"Singlet oxygen addition to chiral allylic alcohols and subsequent peroxyacetalization with ß-naphthaldehyde: Synthesis of diastereomerically pure 3-ß-naphthyl-substituted 1,2,4-trioxanes” Axel G. Griesbeck, Tamer T. El-Idreesy, and Johann Lex, Tetrahedron 2006, 62, 10615-10622.

"Bicyclic Peroxides and Perorthoester with 1,2,4-Trioxane Structures" Axel G. Griesbeck, Dirk Blunk, Tamer El-Idreesy, and Angela Raabe, Angew. Chem. Int. Ed., in the print.